Introducing Calyphi

Precision tools
for scientific data

Calyphi builds open, browser-first tools for researchers. Rigorous statistics, zero data collection, no subscriptions. Start with CurveFit — more instruments coming soon.

CurveFit fitting Michaelis-Menten to enzyme kinetics data
Product #1

CurveFit

Scientific curve fitting — instant, accurate, private.

The problem

GraphPad Prism costs €520 /year. Origin, SigmaPlot, and MATLAB carry similar price tags. For researchers who just need to fit a curve — especially in labs with tight budgets — that's hard to justify.

Meanwhile, free alternatives are either too basic (no model selection, no error estimation) or too complex (scripting in R or Python for every dataset).

Calyphi CurveFit gives you publication-ready fitting in seconds — for free, with no sign-up, and with complete data privacy.

Built for scientists

25+ Models

From linear to Hill, Michaelis-Menten, sigmoidal, power-law, and custom equations.

Levenberg-Marquardt

Gold-standard nonlinear regression with multi-start to avoid local minima.

AICc Model Selection

Akaike weights rank every model — no guessing which curve fits best.

Confidence Bands

≈95 % CI on parameters and prediction bands on the curve, automatically.

100 % Private

Runs entirely in your browser. Zero data ever leaves your device.

Instant Results

Paste data, click fit, done. No install, no account, no waiting.

Ready to fit your data?

No account. No install. Paste your data and get results in seconds.

Open CurveFit — Free

Levenberg–Marquardt optimization · AICc model selection · Akaike weights · Delta-method confidence intervals · Multi-start global search